Geidel Stephan, Lass Michael, Ostermeyer Jörg
Dept. Cardiac Surgery, AK St. Georg Hamburg, Lohmuehlenstrasse 5, 20099 Hamburg, Germany.
Indian Pacing Electrophysiol J. 2005 Oct 1;5(4):254-62.
Even if permanent atrial fibrillation (pAF) is a frequent concomitant problem in patients undergoing open heart surgery and particularly in those with advanced age, data of pAF ablation surgery in older aged patients are scarce. This study was performed to assess early and late results of combined open heart surgery and pAF ablation procedures in patients with advanced aged, compared to young patients.
A selective group of 126 patients (Group A: age =70 [76.4+/-4.8] years, n=70; Group B: age <70 [62.0+/-6.2] years: n=56) with pAF (=6 months) underwent either monopolar (Group A, B: n=51 vs. n=44) or bipolar (Group A, B: n=19 vs. n=12) radiofrequency (RF) ablation procedures concomitant to open heart surgery. Regular follow-up was performed 3 to 36 months after surgery to assess survival, New York Heart Association (NYHA) class and conversion rate to stable sinus rhythm (SR).
Early mortality (<30 days) was 2.9% in Group A (Group B: 0%), cumulative survival at long-term follow up was 0.78 vs. 0.98 (p=0.03) and NYHA-class improved significantly in both groups, particularly in cases with stable SR. At 12-months follow-up 73% of Group A patients were in stable SR (Group B 78%).
Concomitant mono- and bipolar RF ablation surgery represents a safe option to cure pAF during open heart surgery with a very low risk, even in patients with advanced age.
即使永久性心房颤动(pAF)是接受心脏直视手术患者中常见的伴随问题,尤其是老年患者,但老年患者进行pAF消融手术的数据却很稀少。本研究旨在评估老年患者与年轻患者相比,在心脏直视手术联合pAF消融手术中的早期和晚期结果。
选择126例pAF(≥6个月)患者(A组:年龄≥70[76.4±4.8]岁,n = 70;B组:年龄<70[62.0±6.2]岁,n = 56),在心脏直视手术的同时接受单极(A、B组:n = 51 vs. n = 44)或双极(A、B组:n = 19 vs. n = 12)射频(RF)消融手术。术后3至36个月进行定期随访,以评估生存率、纽约心脏协会(NYHA)分级以及转为稳定窦性心律(SR)的转化率。
A组早期死亡率(<30天)为2.9%(B组:0%),长期随访的累积生存率为0.78 vs. 0.98(p = 0.03),两组NYHA分级均显著改善,尤其是在SR稳定的病例中。在12个月随访时,A组73%的患者处于稳定SR(B组为78%)。
即使在老年患者中,单极和双极RF消融手术与心脏直视手术同期进行也是一种低风险的安全治疗pAF的选择。