Geidel Stephan, Ostermeyer Jorg, Lass Michael, Boczor Sigrid, Kuck Karl-Heinz
Department of Cardiac Surgery, AK St.Georg, 20099 Hamburg, Germany.
Indian Pacing Electrophysiol J. 2003 Jul 1;3(3):93-100.
Permanent atrial fibrillation (pAF) is a serious problem in cardiac surgery: An incidence of 3.5% among all patients scheduled for open heart surgery, 9.8% in heart valve cases and 45.6% among patients with severe rheumatic mitral valve (MV) disease was observed in our institution. Our experience with radiofrequency (RF) ablation procedures to treat pAF in these cases is reported.
Since February 2001 monopolar endocardial RF ablation procedures creating two encircling isolation lesions around the left and the right pulmonary veins (LPVs, RPVs) and a connection line between both were performed in patients with pAF concomitant to heart valve surgery. Since March 2003 bipolar RF ablation was used as an adjunct to CABG surgery. Amiodarone was given for 3 months after surgery.
Sixty-two patients with pAF underwent surgical ablation procedures and primary valve (mitral: n=45; aortic: n=13; aortic+mitral: n=1; LA-diameter 55.6+/-7.3 mm) or CABG surgery (n=3). Follow-up was performed at 3, 6, 9, 12, 18 and 24 months; 75% had stable sinus rhythm (SR) at late follow-up. Almost 90% of the patients with a preoperative LA-diameter of <56 mm had SR.
Isolation of the PVs using RF ablation procedures in combination with amiodarone therapy represents a safe and efficient option to cure pAF in patients undergoing open heart surgery.
永久性心房颤动(pAF)是心脏手术中的一个严重问题:在我们机构,所有计划进行心脏直视手术的患者中其发生率为3.5%,心脏瓣膜手术患者中为9.8%,重度风湿性二尖瓣(MV)疾病患者中为45.6%。本文报告了我们在这些病例中使用射频(RF)消融术治疗pAF的经验。
自2001年2月起,对合并心脏瓣膜手术的pAF患者进行单极心内膜RF消融术,在左右肺静脉(LPV、RPV)周围创建两个环绕隔离灶并连接两者。自2003年3月起,双极RF消融术作为冠状动脉旁路移植术(CABG)手术的辅助手段。术后给予胺碘酮治疗3个月。
62例pAF患者接受了手术消融术及初次瓣膜(二尖瓣:n = 45;主动脉瓣:n = 13;主动脉瓣+二尖瓣:n = 1;左心房直径55.6±7.3 mm)或CABG手术(n = 3)。在3、6、9、12、18和24个月进行随访;75%的患者在晚期随访时维持窦性心律(SR)。术前左心房直径<56 mm的患者中近90%有SR。
在接受心脏直视手术的患者中,使用RF消融术隔离肺静脉并联合胺碘酮治疗是治愈pAF的一种安全有效的选择。