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重度慢性牙周病患者接受超声清创术和聚维酮碘治疗后的愈合情况:一项随机对照临床研究。

Healing following ultrasonic debridement and PVP-iodine in individuals with severe chronic periodontal disease: a randomized, controlled clinical study.

作者信息

Leonhardt Asa, Bergström Christina, Krok Lena, Cardaropoli Giuseppe

机构信息

Department of Periodontology, Mölndal Hospital, Mölndal, Sweden.

出版信息

Acta Odontol Scand. 2006 Oct;64(5):262-6. doi: 10.1080/00016350600613625.

DOI:10.1080/00016350600613625
PMID:16945890
Abstract

OBJECTIVE

Antiseptics and antibiotics delivered either locally or systemically have been used as an adjunct to scaling and root planing procedures in order to control the subgingival biofilm and thereby enhancing the treatment outcome. The results presented in the literature are, however, inconclusive. Povidone-iodine (PVP-iodine) has a bactericidal effect and is effective against most bacteria, including putative periodontal pathogens. The aim of the present study was to evaluate the clinical effect of PVP-iodine as an adjunct to ultrasonic scaling in the treatment of severe chronic periodontitis.

MATERIAL AND METHODS

Twenty patients were recruited to the study. Each test site and the related quadrant were randomly assigned to one of four different treatment modalities: ultrasonic scaling + subgingival irrigation with 0.5% PVP-iodine for 5 min/tooth, ultrasonic scaling + subgingival irrigation with sterile saline solution for 5 min/tooth, subgingival irrigation with sterile saline solution for 5 min/tooth, and subgingival irrigation with 0.5% PVP-iodine for 5 min/tooth. The individuals were followed longitudinally for 6 months.

RESULTS

The present study showed that non-surgical periodontal therapy by means of an ultrasonic device was effective in attaining a healthy periodontal status in patients with severe periodontal lesions. No additive effect was found when PVP-iodine was included.

CONCLUSIONS

Ultrasonic debridement using Odontogain is effective in controlling infection in patients with severe chronic periodontitis. PVP-iodine does not add any clinical benefit to the ultrasonic debridement alone under these circumstances.

摘要

目的

局部或全身使用的防腐剂和抗生素已被用作龈下刮治和根面平整程序的辅助手段,以控制龈下生物膜,从而提高治疗效果。然而,文献中给出的结果尚无定论。聚维酮碘(PVP碘)具有杀菌作用,对大多数细菌有效,包括假定的牙周病原体。本研究的目的是评估PVP碘作为辅助超声龈下刮治治疗重度慢性牙周炎的临床效果。

材料与方法

招募20名患者参与研究。每个测试部位及其相关象限被随机分配到四种不同治疗方式中的一种:超声龈下刮治+用0.5%PVP碘龈下冲洗5分钟/颗牙、超声龈下刮治+用无菌盐溶液龈下冲洗5分钟/颗牙、用无菌盐溶液龈下冲洗5分钟/颗牙、用0.5%PVP碘龈下冲洗5分钟/颗牙。对这些个体进行为期6个月的纵向随访。

结果

本研究表明,通过超声设备进行的非手术牙周治疗对患有严重牙周病变的患者有效达到健康的牙周状态。当加入PVP碘时未发现附加效果。

结论

使用Odontogain进行超声清创对重度慢性牙周炎患者控制感染有效。在这些情况下,PVP碘单独对超声清创没有增加任何临床益处。

相似文献

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Healing following ultrasonic debridement and PVP-iodine in individuals with severe chronic periodontal disease: a randomized, controlled clinical study.重度慢性牙周病患者接受超声清创术和聚维酮碘治疗后的愈合情况:一项随机对照临床研究。
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引用本文的文献

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J Clin Med. 2024 Apr 4;13(7):2111. doi: 10.3390/jcm13072111.
2
Efficacy of the Adjunct Use of Povidone-Iodine or Sodium Hypochlorite with Non-Surgical Management of Periodontitis: A Systematic Review and Meta-Analysis.聚维酮碘或次氯酸钠辅助用于牙周炎非手术治疗的疗效:一项系统评价与Meta分析
J Clin Med. 2022 Nov 7;11(21):6593. doi: 10.3390/jcm11216593.
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Antiseptics as adjuncts to scaling and root planing in the treatment of periodontitis: a systematic literature review.
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BMC Oral Health. 2020 May 18;20(1):143. doi: 10.1186/s12903-020-01127-1.
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Commercial Local Pharmacotherapeutics and Adjunctive Agents for Nonsurgical Treatment of Periodontitis: A Contemporary Review of Clinical Efficacies and Challenges.用于牙周炎非手术治疗的商业局部药物治疗方法及辅助药物:临床疗效与挑战的当代综述
Antibiotics (Basel). 2019 Dec 30;9(1):11. doi: 10.3390/antibiotics9010011.
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Effectiveness of Subgingival Irrigation as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis: A Systematic Review.龈下冲洗作为刮治术和根面平整术辅助治疗慢性牙周炎的有效性:一项系统评价
J Clin Diagn Res. 2015 Jul;9(7):ZE06-9. doi: 10.7860/JCDR/2015/13862.6210. Epub 2015 Jul 1.
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Full-mouth ultrasonic debridement associated with povidone iodine rinsing in GAgP treatment: a randomised clinical trial.全口超声清创联合聚维酮碘冲洗在侵袭性牙周炎治疗中的应用:一项随机临床试验。
Clin Oral Investig. 2016 Jan;20(1):141-50. doi: 10.1007/s00784-015-1471-y. Epub 2015 Apr 16.