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重度慢性牙周病患者接受超声清创术和聚维酮碘治疗后的愈合情况:一项随机对照临床研究。

Healing following ultrasonic debridement and PVP-iodine in individuals with severe chronic periodontal disease: a randomized, controlled clinical study.

作者信息

Leonhardt Asa, Bergström Christina, Krok Lena, Cardaropoli Giuseppe

机构信息

Department of Periodontology, Mölndal Hospital, Mölndal, Sweden.

出版信息

Acta Odontol Scand. 2006 Oct;64(5):262-6. doi: 10.1080/00016350600613625.

Abstract

OBJECTIVE

Antiseptics and antibiotics delivered either locally or systemically have been used as an adjunct to scaling and root planing procedures in order to control the subgingival biofilm and thereby enhancing the treatment outcome. The results presented in the literature are, however, inconclusive. Povidone-iodine (PVP-iodine) has a bactericidal effect and is effective against most bacteria, including putative periodontal pathogens. The aim of the present study was to evaluate the clinical effect of PVP-iodine as an adjunct to ultrasonic scaling in the treatment of severe chronic periodontitis.

MATERIAL AND METHODS

Twenty patients were recruited to the study. Each test site and the related quadrant were randomly assigned to one of four different treatment modalities: ultrasonic scaling + subgingival irrigation with 0.5% PVP-iodine for 5 min/tooth, ultrasonic scaling + subgingival irrigation with sterile saline solution for 5 min/tooth, subgingival irrigation with sterile saline solution for 5 min/tooth, and subgingival irrigation with 0.5% PVP-iodine for 5 min/tooth. The individuals were followed longitudinally for 6 months.

RESULTS

The present study showed that non-surgical periodontal therapy by means of an ultrasonic device was effective in attaining a healthy periodontal status in patients with severe periodontal lesions. No additive effect was found when PVP-iodine was included.

CONCLUSIONS

Ultrasonic debridement using Odontogain is effective in controlling infection in patients with severe chronic periodontitis. PVP-iodine does not add any clinical benefit to the ultrasonic debridement alone under these circumstances.

摘要

目的

局部或全身使用的防腐剂和抗生素已被用作龈下刮治和根面平整程序的辅助手段,以控制龈下生物膜,从而提高治疗效果。然而,文献中给出的结果尚无定论。聚维酮碘(PVP碘)具有杀菌作用,对大多数细菌有效,包括假定的牙周病原体。本研究的目的是评估PVP碘作为辅助超声龈下刮治治疗重度慢性牙周炎的临床效果。

材料与方法

招募20名患者参与研究。每个测试部位及其相关象限被随机分配到四种不同治疗方式中的一种:超声龈下刮治+用0.5%PVP碘龈下冲洗5分钟/颗牙、超声龈下刮治+用无菌盐溶液龈下冲洗5分钟/颗牙、用无菌盐溶液龈下冲洗5分钟/颗牙、用0.5%PVP碘龈下冲洗5分钟/颗牙。对这些个体进行为期6个月的纵向随访。

结果

本研究表明,通过超声设备进行的非手术牙周治疗对患有严重牙周病变的患者有效达到健康的牙周状态。当加入PVP碘时未发现附加效果。

结论

使用Odontogain进行超声清创对重度慢性牙周炎患者控制感染有效。在这些情况下,PVP碘单独对超声清创没有增加任何临床益处。

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