Early development of boys with Duchenne muscular dystrophy.

Thirty-three boys with Duchenne muscular dystrophy (DMD) and a mean age of 3.4 years were assessed with the Griffiths Developmental Scales, the Reynell Language Scales and the British Picture Vocabulary Scales at six-monthly intervals over a one-year period. The boys showed developmental delay, which was most severe in the locomotor and language areas. The locomotor quotients deteriorated over time, but the other quotients did not. Maternal intelligence, home environment and social class had little effect on the aetiology of the developmental delay, and the behavioural problems seen in young boys with DMD may be secondary to it.