Dang Yen, Mercer Dale
Department of Surgery, Kingston General Hospital, Queen's University, Kingston, ON.
Can J Surg. 2006 Aug;49(4):267-71.
Prospective randomized studies have suggested that surgery palliates esophageal achalasia more effectively than pneumatic dilatation, but for some dilatation is still the procedure of choice for initial treatment. We decided to compare achalasia symptoms before and after Heller myotomy by means of postoperative questionnaires.
The study included 22 patients who underwent Heller myotomy for achalasia at the Hotel Dieu Hospital, Queen's University, Kingston, Ont., since July 1990; 5 of them required repeat myotomy for symptom recurrence, for a total of 9 open and 18 laparoscopic procedures. Median follow-up was 43 (range 6-109) months. Preoperative and postoperative data regarding dysphagia, regurgitation, chest pain and overall patient satisfaction were gathered. Symptom scores were calculated by adding severity (0 = none, 2 = mild, 4 = moderate, 6 = severe) to frequency (0 = never, 1 = occasionally, 2 = once a month, 3 = every week, 4 = twice a week, 5 = daily). Patients having a repeat procedure were instructed to evaluate symptoms with respect to their initial myotomy.
Seventeen (77%) patients were successfully contacted, 4 of them had subsequent repeat myotomy for symptom recurrence. Initially, overall symptom scores decreased for all but 1 patient, with mean preoperative and postoperative values of 23.1 and 7.3 respectively (p < 0.001). The patient in whom symptoms did not improve is a candidate for a repeat procedure. Repeat myotomy was performed after a median of 38 (range 23-75) months, corresponding to an overall 3-year positive outcome in 13 (76%) of the 17 patients. Fifteen (88%) patients considered their myotomies a success and 16 (94%) would choose to have this procedure again given the outcome.
Heller myotomy appears to be effective in alleviating the symptoms of achalasia. Repeat myotomy is occasionally required.
前瞻性随机研究表明,手术治疗贲门失弛缓症比气囊扩张更有效,但对于一些患者来说,扩张仍是初始治疗的首选方法。我们决定通过术后问卷调查来比较贲门肌切开术前后的失弛缓症症状。
该研究纳入了自1990年7月起在安大略省金斯顿女王大学迪厄医院接受贲门肌切开术治疗失弛缓症的22例患者;其中5例因症状复发需要再次进行肌切开术,总共进行了9例开放手术和18例腹腔镜手术。中位随访时间为43(6 - 109)个月。收集了术前和术后关于吞咽困难、反流、胸痛及患者总体满意度的数据。症状评分通过将严重程度(0 = 无,2 = 轻度,4 = 中度,6 = 重度)与频率(0 = 从不,1 = 偶尔,2 = 每月一次,3 = 每周一次,4 = 每周两次,5 = 每天)相加得出。接受再次手术的患者被要求根据其初次肌切开术来评估症状。
成功联系到17例(77%)患者,其中4例因症状复发随后进行了再次肌切开术。最初,除1例患者外,所有患者的总体症状评分均下降,术前和术后的平均评分别为23.1和7.3(p < 0.001)。症状未改善的患者是再次手术的候选对象。再次肌切开术在中位时间38(23 - 75)个月后进行,这使得17例患者中的13例(76%)在总体3年时获得了阳性结果。15例(88%)患者认为他们的肌切开术是成功的,16例(94%)患者表示鉴于结果会再次选择该手术。
贲门肌切开术似乎能有效缓解失弛缓症症状。偶尔需要进行再次肌切开术。