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贲门失弛缓症开放手术与腹腔镜食管肌层切开术治疗效果的比较。

Comparison of outcomes following open and laparoscopic esophagomyotomy for achalasia.

作者信息

Dempsey D T, Kalan M M, Gerson R S, Parkman H P, Maier W P

机构信息

Departments of Surgery and Gastroenterology, Temple University Hospital, Parkinson Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA.

出版信息

Surg Endosc. 1999 Aug;13(8):747-50. doi: 10.1007/s004649901091.

Abstract

BACKGROUND

Minimally invasive esophagomyotomy is replacing open surgery for achalasia, but data comparing these procedures performed by the same surgical team are sparse. The purpose of this study was to compare the morbidity and clinical outcome following laparoscopic and open esophagomyotomy.

METHODS

Twelve consecutive patients referred for elective surgery between August 1995 and August 1997 underwent laparoscopic myotomy and partial fundoplication. They were compared to a group of 10 patients chosen from a larger pool of 20 patients who had open surgery during the same period performed by our own group. The mean length of follow-up in the laparoscopic group was 16 months; in the open group, it was 60 months. Both groups had similar demographics and clinical features. Each patient had at least one previous pneumatic dilatation. Inpatient records were reviewed. Patients were interviewed using a symptom assessment and patient satisfaction questionnaire.

RESULTS

As compared to the open operation, laparoscopic esophagomyotomy with partial fundoplication resulted in significantly (p < 0.05) less blood loss (50 +/- 26 cc versus 220 +/- 127 cc), parenteral narcotic use (2.1 +/- 1.0 days versus 5.3 +/- 1.4 days), time in hospital (2.7 +/- 1.0 days versus 8.8 +/- 2.6 days), and time off work (19 +/- 16 days versus 85 +/- 60 days). There were similar results for the laparoscopic and open groups in the improvement in dysphagia (92% versus 90%) and patient satisfaction with surgery (84% versus 80%).

CONCLUSIONS

Laparoscopic esophagomyotomy for achalasia results in symptomatic improvement and high patient satisfaction comparable to the open procedure but with significantly less morbidity.

摘要

背景

微创食管肌层切开术正在取代贲门失弛缓症的开放手术,但由同一手术团队实施这两种手术的比较数据较少。本研究的目的是比较腹腔镜和开放食管肌层切开术后的发病率和临床结局。

方法

1995年8月至1997年8月期间连续12例接受择期手术的患者接受了腹腔镜肌层切开术和部分胃底折叠术。将他们与从同期由我们团队进行开放手术的20例患者中选出的10例患者组成的小组进行比较。腹腔镜组的平均随访时间为16个月;开放组为60个月。两组的人口统计学和临床特征相似。每位患者此前至少接受过一次气囊扩张术。回顾了住院记录。使用症状评估和患者满意度问卷对患者进行了访谈。

结果

与开放手术相比,腹腔镜食管肌层切开术加部分胃底折叠术导致失血量显著减少(50±26毫升对220±127毫升,p<0.05)、胃肠外麻醉使用时间显著减少(2.1±1.0天对5.3±1.4天)、住院时间显著减少(2.7±1.0天对8.8±2.6天)以及误工时间显著减少(19±16天对85±60天)。腹腔镜组和开放组在吞咽困难改善方面(92%对90%)以及患者对手术的满意度方面(84%对80%)结果相似。

结论

腹腔镜贲门失弛缓症食管肌层切开术在症状改善和患者满意度方面与开放手术相当,但发病率显著更低。

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