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蒲公英——关于其植物化学和药理特性的综述。

Taraxacum--a review on its phytochemical and pharmacological profile.

作者信息

Schütz Katrin, Carle Reinhold, Schieber Andreas

机构信息

Institute of Food Technology, Section Plant Foodstuff Technology, Hohenheim University, August-von-Hartmann-Strasse 3, D-70599 Stuttgart, Germany.

出版信息

J Ethnopharmacol. 2006 Oct 11;107(3):313-23. doi: 10.1016/j.jep.2006.07.021. Epub 2006 Jul 22.

DOI:10.1016/j.jep.2006.07.021
PMID:16950583
Abstract

The genus Taraxacum is a member of the family Asteraceae, subfamily Cichorioideae, tribe Lactuceae and widely distributed in the warmer temperate zones of the Northern Hemisphere. The perennial weed has been known since ancient times for its curative properties and has been utilized for the treatment of various ailments such as dyspepsia, heartburn, spleen and liver complaints, hepatitis and anorexia. However, its use has mainly been based on empirical findings. This contribution provides a comprehensive review of the pharmacologically relevant compounds of Taraxacum characterized so far and of the studies supporting its use as a medicinal plant. Particular attention has been given to diuretic, choleretic, anti-inflammatory, anti-oxidative, anti-carcinogenic, analgesic, anti-hyperglycemic, anti-coagulatory and prebiotic effects. Finally, research needs such as quantification of individual Taraxacum constituents and assessment of their pharmacological activities in humans have briefly been outlined.

摘要

蒲公英属是菊科、菊苣亚科、莴苣族的成员,广泛分布于北半球较温暖的温带地区。这种多年生杂草自古以来就因其治疗功效而闻名,并已被用于治疗各种疾病,如消化不良、胃灼热、脾脏和肝脏疾病、肝炎和厌食症。然而,其用途主要基于经验发现。本文对迄今为止已鉴定的蒲公英的药理活性成分以及支持其作为药用植物的研究进行了全面综述。特别关注了其利尿、利胆、抗炎、抗氧化、抗癌、镇痛、抗高血糖、抗凝血和益生元作用。最后,简要概述了一些研究需求,如对蒲公英各成分进行定量分析以及评估其在人体中的药理活性。

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