感染鼠贾第虫的小鼠派伊尔结中的淋巴细胞增殖
Lymphocyte proliferation in Peyer's patches of Giardia muris-infected mice.
作者信息
Hill D R
机构信息
Department of Medicine, University of Connecticut School of Medicine, Farmington 06032.
出版信息
Infect Immun. 1990 Aug;58(8):2683-5. doi: 10.1128/iai.58.8.2683-2685.1990.
Abstract
Gastrointestinal immune events in giardiasis are important in controlling infection. In this study, Peyer's patch lymphocytes from mice infected with Giardia muris developed specific, proliferative responses to G. muris antigen. This proliferation correlated with clearance of infection. Further understanding of the gut immune response will be helpful in developing immunoprophylactic strategies in the control of giardiasis.
摘要
贾第虫病中的胃肠道免疫事件在控制感染方面很重要。在本研究中，感染鼠贾第虫的小鼠派尔集合淋巴结淋巴细胞对鼠贾第虫抗原有特异性增殖反应。这种增殖与感染清除相关。进一步了解肠道免疫反应将有助于制定控制贾第虫病的免疫预防策略。
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