PC12细胞的分化

Differentiation of PC12 cells.

作者信息

Adler Elizabeth M, Gough Nancy R, Blundon Jay A

机构信息

American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

出版信息

Sci STKE. 2006 Sep 5;2006(351):tr9. doi: 10.1126/stke.3512006tr9.

DOI:10.1126/stke.3512006tr9

PMID:16954573

Abstract

This 3-week-long series of collaborative laboratory exercises explores how to use a cultured cell system (PC12 cells) to study signaling pathways involved in cellular differentiation. The laboratory would be useful in a neurobiology or cell biology course for advanced undergraduate students. The background and details for performing the lab are provided along with suggestions for assessing student performance and understanding.

摘要

这个为期3周的系列协作实验室练习探索了如何使用培养的细胞系统（PC12细胞）来研究细胞分化中涉及的信号通路。该实验室对本科高年级学生的神经生物学或细胞生物学课程会很有用。文中提供了进行该实验的背景和细节，以及评估学生表现和理解情况的建议。