Wessels-van Middendorp A M, Timmerman L
Tijdschr Psychiatr. 2006;48(3):229-34.
The subject of this case study is a female patient who was treated with a selective serotonin reuptake inhibitor (SSRI), citalopram, because of a depressive episode. She developed symptoms of galactorrhea; there was a time relationship between suspension of the treatment with citalopram and a reduction of the galactorrhea symptoms. The consulting internist assumed that the symptoms were due to hyperprolactinemia arising from under-supplementation of thyroid hormone and resultant hypothyroidism. Psychiatrists usually see galactorrhea in patients who are taking antipsychotics. However, few psychiatrists know that galactorrhea can also be caused by SSRIs. When a patient has symptoms of bilateral galactorrhea and has used an SSRI and when hyperprolactinemia has been found in laboratory tests it is probably advisable to stop the SSRI medication. The article mentions what additional research is needed.
本案例研究的对象是一名女性患者，她因抑郁发作接受了选择性5-羟色胺再摄取抑制剂（SSRI）西酞普兰的治疗。她出现了溢乳症状；停用西酞普兰治疗与溢乳症状减轻之间存在时间关联。会诊的内科医生认为这些症状是由于甲状腺激素补充不足导致甲状腺功能减退进而引起的高催乳素血症所致。精神科医生通常会在服用抗精神病药物的患者中见到溢乳症状。然而，很少有精神科医生知道溢乳也可能由SSRI引起。当患者出现双侧溢乳症状且使用过SSRI，并且实验室检查发现高催乳素血症时，可能明智的做法是停用SSRI药物。文章提到了还需要哪些额外的研究。
