利培酮 - 氟伏沙明联合使用导致的正常催乳素血症性男性乳房发育和溢乳
Euprolactinemic gynecomastia and galactorrhea with risperidone-fluvoxamine combination.
作者信息
Pratheesh P J, Praharaj Samir Kumar, Srivastava Ashish
机构信息
Department of Psychiatry, Kasturba Medical College, Manipal, Karnataka, India.
出版信息
Psychopharmacol Bull. 2011;44(1):70-3.
Abstract
Risperidone is associated with hyperprolactinemia and its consequent symptoms such as gynecomastia, galactorrhea and sexual dysfunction in adults, and less so in adolescents. Rarely, serotonin reuptake inhibitors are also associated with such adverse effects. We report a case of gynecomastia and galactorrhea in an adolescent male while on a combination of risperidone and fluvoxamine, although the serum prolactin was within normal range.
摘要
利培酮与高催乳素血症及其相关症状有关，如成年男性的乳腺增生、溢乳和性功能障碍，在青少年中则较少见。很少有情况是，血清素再摄取抑制剂也会出现此类不良反应。我们报告了一例青少年男性在服用利培酮和氟伏沙明联合用药期间出现乳腺增生和溢乳的病例，尽管其血清催乳素水平在正常范围内。
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本文引用的文献
1
Differential add-on effects of aripiprazole in resolving hyperprolactinemia induced by risperidone in comparison to benzamide antipsychotics.与苯酰胺类抗精神病药相比，阿立哌唑在解决利培酮引起的高催乳素血症方面的附加效应差异。
Prog Neuropsychopharmacol Biol Psychiatry. 2010 Dec 1;34(8):1495-9. doi: 10.1016/j.pnpbp.2010.08.012. Epub 2010 Aug 20.
2
A case of galactorrhea associated with excitalopram.与艾司西酞普兰相关的溢乳病例。
Psychiatry Investig. 2009 Sep;6(3):230-2. doi: 10.4306/pi.2009.6.3.230. Epub 2009 Jul 15.
3
A case with euprolactinemic galactorrhea induced by escitalopram.一例由艾司西酞普兰引起的催乳素正常性溢乳症病例。
Int J Psychiatry Med. 2007;37(3):275-8. doi: 10.2190/PM.37.3.d.
4
Risperidone-induced symptomatic hyperprolactinaemia in adolescents.利培酮诱发青少年出现症状性高催乳素血症。
J Clin Psychopharmacol. 2006 Apr;26(2):167-71. doi: 10.1097/01.jcp.0000203194.58087.9a.
5
Effect of fluvoxamine on plasma risperidone concentrations in patients with schizophrenia.
Pharmacol Res. 2005 Dec;52(6):497-501. doi: 10.1016/j.phrs.2005.09.005. Epub 2005 Oct 11.
6
Low-dose risperidone augmentation of fluvoxamine treatment in obsessive-compulsive disorder: a double-blind, placebo-controlled study.低剂量利培酮增强氟伏沙明治疗强迫症：一项双盲、安慰剂对照研究。
Eur Neuropsychopharmacol. 2005 Jan;15(1):69-74. doi: 10.1016/j.euroneuro.2004.04.004.
7
Antipsychotic-induced hyperprolactinaemia: mechanisms, clinical features and management.抗精神病药物所致高催乳素血症：机制、临床特征及管理
Drugs. 2004;64(20):2291-314. doi: 10.2165/00003495-200464200-00003.
8
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J Clin Psychiatry. 2003 Nov;64(11):1362-9. doi: 10.4088/jcp.v64n1113.
9
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Mayo Clin Proc. 2001 Feb;76(2):215-6. doi: 10.1016/S0025-6196(11)63132-7.
10
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J Clin Psychopharmacol. 1999 Feb;19(1):57-61. doi: 10.1097/00004714-199902000-00011.
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