Peterson M C
Division of General Internal Medicine, University of Utah School of Medicine, Salt Lake City, USA.
Mayo Clin Proc. 2001 Feb;76(2):215-6. doi: 10.1016/S0025-6196(11)63132-7.
Fluoxetine, an antidepressant of the selective serotonin reuptake inhibitor class, may stimulate prolactin release by pituitary lactotrophs. A 71-year-old woman taking estrogen replacement therapy developed galactorrhea after initiation of fluoxetine for depression and was found to have an elevated prolactin level. Fluoxetine was discontinued with resolution of the patient's galactorrhea and normalization of her prolactin level.
氟西汀是一种选择性5-羟色胺再摄取抑制剂类抗抑郁药，它可能会刺激垂体催乳细胞释放催乳素。一名正在接受雌激素替代疗法的71岁女性在开始服用氟西汀治疗抑郁症后出现了溢乳现象，并且发现其催乳素水平升高。停用氟西汀后，该患者的溢乳现象消失，催乳素水平恢复正常。
