Thomas Karen A, Burr Robert L
Department of Family and Child Nursing in the University of Washington, Seattle, USA.
J Obstet Gynecol Neonatal Nurs. 2006 Sep-Oct;35(5):608-15. doi: 10.1111/j.1552-6909.2006.00082.x.
To compare 24-hour melatonin level and timing in postpartum and nonpregnant nulliparous women. Melatonin release provides information regarding circadian rhythm timing, which influences health.
2-group comparison of data derived from intensive within-subject data collection.
Participants' typical daily environment.
38 postpartum and 20 nonpregnant nulliparous women. Mothers' infants were 4 to 10 weeks of postnatal age.
Urinary 6-sulfatoxymelatonin assayed from each voiding and corrected for volume using creatinine.
Postpartum women had significantly higher baseline, lower maximum, lower percent rise, and differing pattern of 6-sulfatoxymelatonin than nonpregnant nulliparous women.
Differences in melatonin suggest possible circadian rhythm disruption in the postnatal period.
比较产后女性与未孕未育女性的24小时褪黑素水平及分泌时间。褪黑素的释放提供了有关昼夜节律时间的信息，而昼夜节律会影响健康。
对来自密集的受试者内数据收集的两组数据进行比较。
参与者的日常典型环境。
38名产后女性和20名未孕未育女性。产妇的婴儿出生后4至10周。
检测每次排尿的尿6-硫酸氧褪黑素，并使用肌酐校正尿量。
与未孕未育女性相比，产后女性的6-硫酸氧褪黑素基线水平显著更高，最高水平更低，升高百分比更低，且分泌模式不同。
褪黑素的差异表明产后可能存在昼夜节律紊乱。
