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单纯孔源性视网膜脱离手术干预的循证分析

An evidence-based analysis of surgical interventions for uncomplicated rhegmatogenous retinal detachment.

作者信息

Saw Seang-Mei, Gazzard Gus, Wagle Ajeet M, Lim Jimmy, Au Eong Kah-Guan

机构信息

Department of Community, Occupational and Family Medicine, National University of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

出版信息

Acta Ophthalmol Scand. 2006 Oct;84(5):606-12. doi: 10.1111/j.1600-0420.2006.00715.x.

Abstract

PURPOSE

To evaluate the various surgical interventions available for uncomplicated rhegmatogenous retinal detachment.

METHODS

Reports of controlled clinical trials of surgical interventions (pneumatic retinopexy, scleral buckling and vitrectomy) for uncomplicated rhegmatogenous retinal detachment indexed in MEDLINE from 1968 to January 2006 were included. The primary outcomes evaluated included single-operation reattachment rates, multiple reoperation reattachment rates and improvements in visual acuity (VA).

RESULTS

We found five controlled trials (two randomized) comparing the efficacy of pneumatic retinopexy versus scleral buckling. The single-operation reattachment rates were higher for scleral buckling, but the final reattachment rates were similar. We found nine controlled trials (four randomized) evaluating vitrectomy. There were no statistically significant differences between retinal reattachment rates or final visual acuities, except in one randomized and one non-randomized controlled trial in which the VAs were significantly better in the vitrectomy than the scleral buckling group.

CONCLUSIONS

Pneumatic retinopexy is a possible alternative to scleral buckling in the treatment of uncomplicated rhegmatogenous retinal detachment. The rates of missed or new retinal breaks after pneumatic retinopexy, however, are higher than following scleral buckling. The clinical outcomes of vitrectomy for rhegmatogenous retinal detachment compare favourably.

摘要

目的

评估用于单纯孔源性视网膜脱离的各种手术干预措施。

方法

纳入1968年至2006年1月在MEDLINE中索引的关于单纯孔源性视网膜脱离的手术干预措施(气体视网膜固定术、巩膜扣带术和玻璃体切除术)的对照临床试验报告。评估的主要结果包括单次手术复位率、多次再次手术复位率和视力(VA)改善情况。

结果

我们发现五项对照试验(两项随机试验)比较了气体视网膜固定术与巩膜扣带术的疗效。巩膜扣带术的单次手术复位率较高,但最终复位率相似。我们发现九项评估玻璃体切除术的对照试验(四项随机试验)。视网膜复位率或最终视力之间无统计学显著差异,但在一项随机对照试验和一项非随机对照试验中,玻璃体切除术组的视力明显优于巩膜扣带术组。

结论

在治疗单纯孔源性视网膜脱离时,气体视网膜固定术是巩膜扣带术的一种可能替代方法。然而,气体视网膜固定术后遗漏或新出现视网膜裂孔的发生率高于巩膜扣带术。孔源性视网膜脱离的玻璃体切除临床效果较好。

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