Sharma Yog Raj, Karunanithi Sathiyan, Azad Raj Vardhan, Vohra Rajpal, Pal Nikhil, Singh Deependra Vikram, Chandra Parijat
Vitreo-Retina Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Acta Ophthalmol Scand. 2005 Jun;83(3):293-7. doi: 10.1111/j.1600-0420.2005.00461.x.
To conduct a randomized prospective clinical trial to compare primary vitrectomy without scleral buckling versus conventional scleral buckling surgery in pseudophakic primary retinal detachment (PPRD) in terms of anatomic attachment rate, functional outcome and complications.
Fifty consecutive eyes of 50 patients with PPRD were randomized into two groups, with 25 patients in each of group 1 (scleral buckling group) and group 2 (pars plana vitrectomy without buckling group) in a hospital setting and followed up at 1 week, 2 weeks, 6 weeks and 6 months.
A primary reattachment rate of 76% (19 retinas) was obtained in group 1, while a reattachment rate of 84% (21 retinas) was achieved in group 2. The final anatomic reattachment rate was 100% in both groups. The causes of failure in group 1 were proliferative vitreoretinopathy in five eyes and open break/missed break in one eye. The causes of failure in group 2 were missed break/open break in three eyes and proliferative vitreoretinopathy in one eye. Best corrected visual acuity (BCVA) at 2 weeks was better in group 1, while the final BCVA at end of 6 months was two lines better in group 2. The mean change in refractive error was -- 1.38 D in group 1 and -- 0.85 D in group 2.
Pars plana vitrectomy without buckling provides an effective treatment for PPRD and results in better longterm visual and anatomic outcomes than conventional scleral buckling.
进行一项随机前瞻性临床试验,比较无巩膜扣带的原发性玻璃体切除术与传统巩膜扣带手术治疗人工晶状体眼原发性视网膜脱离(PPRD)的解剖复位率、功能预后及并发症。
将50例PPRD患者的50只连续患眼随机分为两组,在医院环境中,第1组(巩膜扣带组)和第2组(无扣带的扁平部玻璃体切除术组)各25例,分别于术后1周、2周、6周和6个月进行随访。
第1组的原发性复位率为76%(19只视网膜),而第2组的复位率为84%(21只视网膜)。两组的最终解剖复位率均为100%。第1组失败的原因是5只眼发生增殖性玻璃体视网膜病变,1只眼出现开放性裂孔/遗漏裂孔。第2组失败的原因是3只眼出现遗漏裂孔/开放性裂孔,1只眼发生增殖性玻璃体视网膜病变。第1组术后2周的最佳矫正视力(BCVA)较好,而第2组术后6个月末的最终BCVA提高了两行。第1组屈光不正的平均变化为-1.38D,第2组为-0.85D。
无扣带的扁平部玻璃体切除术为PPRD提供了一种有效的治疗方法,与传统巩膜扣带术相比,其长期视觉和解剖效果更好。