1981年至1999年佛罗里达州职业消防员的癌症发病率。

Cancer incidence in Florida professional firefighters, 1981 to 1999.

作者信息

Ma Fangchao, Fleming Lora E, Lee David J, Trapido Edward, Gerace Terence A

机构信息

Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida, USA.

出版信息

J Occup Environ Med. 2006 Sep;48(9):883-8. doi: 10.1097/01.jom.0000235862.12518.04.

DOI:10.1097/01.jom.0000235862.12518.04

PMID:16966954

Abstract

OBJECTIVE

The objective of this study was to examine the cancer risk associated with firefighting.

METHODS

Standardized incidence ratio analysis (SIR) was used to determine the relative cancer risk for firefighters as compared with the Florida general population.

RESULTS

Among 34,796 male (413,022 person-years) and 2,017 female (18,843 person-years) firefighters, 970 male and 52 female cases of cancer were identified. Male firefighters had significantly increased incidence rates of bladder (SIR = 1.29; 95% confidence interval = 1.01-1.62), testicular (1.60; 1.20-2.09), and thyroid cancers (1.77; 1.08-2.73). Female firefighters had significantly increased incidence rates of overall cancer (1.63; 1.22-2.14), cervical (5.24; 2.93-8.65), and thyroid cancer (3.97; 1.45-8.65) and Hodgkin disease (6.25; 1.26-18.26).

CONCLUSIONS

Firefighting may be associated with an increased risk of selected site-specific cancers in males and females, including an overall increased cancer risk in female firefighters.

摘要

目的

本研究的目的是调查与消防工作相关的癌症风险。

方法

采用标准化发病比分析（SIR）来确定消防员相对于佛罗里达州普通人群的相对癌症风险。

结果

在34796名男性消防员（413022人年）和2017名女性消防员（18843人年）中，确诊了970例男性癌症病例和52例女性癌症病例。男性消防员膀胱癌（SIR = 1.29；95%置信区间 = 1.01 - 1.62）、睾丸癌（1.60；1.20 - 2.09）和甲状腺癌（1.77；1.08 - 2.73）的发病率显著增加。女性消防员总体癌症（1.63；1.22 - 2.14）、宫颈癌（5.24；2.93 - 8.65）、甲状腺癌（3.97；1.45 - 8.65）和霍奇金病（6.25；1.26 - 18.26）的发病率显著增加。