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积水是否预示着严重的膀胱输尿管反流的存在?

Does hydronephrosis predict the presence of severe vesicoureteral reflux?

机构信息

Pediatric Nephrology Division, College of Medicine, University of Florida, PO Box 100296, Gainesville, FL 32610, USA.

出版信息

Eur J Pediatr. 2012 Nov;171(11):1605-10. doi: 10.1007/s00431-012-1775-8. Epub 2012 Jun 27.

Abstract

UNLABELLED

We hypothesized that, in patients with vesicoureteral reflux (VUR) grade IV or V, hydronephrosis will likely be found, if the patient has a full bladder during the renal ultrasound examination. Eight hundred thirty-seven patients were included in the study. Patients ranged in age from <1 month to 18.7 years, with a median age of 1.3 years. Five hundred sixty-nine were female and 268 were male. In this retrospective study, each patient underwent a voiding cystourethrogram (VCUG) and a renal ultrasound examination. The presence of hydronephrosis and bladder filling status in 131 renal units with VUR grade IV or V was evaluated. Sensitivity and specificity for hydronephrosis to detect the presence of VUR grades IV and V were 60 and 92 %, respectively. Positive predictive value and negative predictive value were 74 and 87 %, respectively. Odds ratios for the relationship between hydronephrosis and severe VUR was significant (p = 0.046).

CONCLUSION

In patients with grade IV or V VUR, hydronephrosis will be observed in the presence of a full bladder. Therefore, a renal ultrasound could be considered a screening test to decide on performing a VCUG.

摘要

目的

我们假设,如果在进行肾脏超声检查时患者膀胱充盈,那么患有四级或五级膀胱输尿管反流(VUR)的患者很可能会出现肾积水。

方法

本研究纳入了 837 例患者。患者年龄从<1 个月至 18.7 岁不等,中位年龄为 1.3 岁。其中 569 例为女性,268 例为男性。在这项回顾性研究中,每位患者均接受了排尿性膀胱尿道造影(VCUG)和肾脏超声检查。评估了 131 个存在四级或五级 VUR 的肾脏单位的肾积水和膀胱充盈情况。肾积水检测四级和五级 VUR 的敏感性和特异性分别为 60%和 92%。阳性预测值和阴性预测值分别为 74%和 87%。肾积水与严重 VUR 之间的关系的优势比具有统计学意义(p=0.046)。

结论

在患有四级或五级 VUR 的患者中,当膀胱充盈时会出现肾积水。因此,肾脏超声检查可作为决定是否进行 VCUG 的筛选检查。

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