Malbrain Manu L N G, Cheatham Michael L, Kirkpatrick Andrew, Sugrue Michael, Parr Michael, De Waele Jan, Balogh Zsolt, Leppäniemi Ari, Olvera Claudia, Ivatury Rao, D'Amours Scott, Wendon Julia, Hillman Ken, Johansson Kenth, Kolkman Karel, Wilmer Alexander
Department of Intensive Care, Ziekenhuis Netwerk Antwerpen, Campus Stuivenberg, Lange Beeldekensstraat 267, 2060, Antwerpen 6, Belgium.
Intensive Care Med. 2006 Nov;32(11):1722-32. doi: 10.1007/s00134-006-0349-5. Epub 2006 Sep 12.
Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) have been increasingly recognized in the critically ill over the past decade. The variety of definitions proposed has led to confusion and difficulty in comparing one study to another.
An international consensus group of critical care specialists convened at the second World Congress on Abdominal Compartment Syndrome to standardize definitions for IAH and ACS based upon the current understanding of the pathophysiology surrounding these two syndromes.
Prior to the conference the authors developed a blueprint for the various definitions, which was further refined both during and after the conference. The present article serves as the final report of the 2004 International ACS Consensus Definitions Conference and is endorsed by the World Society of Abdominal Compartment Syndrome (WSACS).
IAH is redefined as an intra-abdominal pressure (IAP) at or above 12 mmHg. ACS is redefined as an IAP above 20 mmHg with evidence of organ dysfunction/failure. ACS is further classified as either primary, secondary, or recurrent based upon the duration and cause of the IAH-induced organ failure. Standards for IAP monitoring are set forth to facilitate accuracy of IAP measurements from patient to patient.
State-of-the-art definitions for IAH and ACS are proposed based upon current medical evidence as well as expert opinion. The WSACS recommends that these definitions be used for future clinical and basic science research. Specific guidelines and recommendations for clinical management of patients with IAH/ACS are published in a separate review.
在过去十年中,危重病患者的腹腔内高压(IAH)和腹腔间隔室综合征(ACS)越来越受到关注。提出的多种定义导致了研究之间进行比较时的混乱和困难。
一个由重症监护专家组成的国际共识小组在第二届腹腔间隔室综合征世界大会上召开会议,根据目前对这两种综合征病理生理学的理解,对IAH和ACS的定义进行标准化。
会议召开前,作者制定了各种定义的蓝图,并在会议期间和会后进一步完善。本文作为2004年国际ACS共识定义会议的最终报告,得到了世界腹腔间隔室综合征协会(WSACS)的认可。
IAH被重新定义为腹腔内压力(IAP)等于或高于12 mmHg。ACS被重新定义为IAP高于20 mmHg且伴有器官功能障碍/衰竭的证据。根据IAH诱发器官衰竭的持续时间和原因,ACS进一步分为原发性、继发性或复发性。制定了IAP监测标准,以促进不同患者IAP测量的准确性。
基于当前医学证据和专家意见,提出了IAH和ACS的最新定义。WSACS建议将这些定义用于未来的临床和基础科学研究。关于IAH/ACS患者临床管理的具体指南和建议发表在另一篇综述中。