基于辐射致免疫抑制模型对脂多糖和硫酸葡聚糖免疫刺激特性的研究
[Studies of the immunostimulating properties of lipopolysaccharides and dextran sulfate based on a model of radiogenic immunodepression].
作者信息
Prokofjev S A, Perelygin N L, Dmitrijeva N B, Markina E V, Utesev B S
机构信息
2. Moskauer Medizinisches Institut, UdSSR.
出版信息
Radiobiol Radiother (Berl). 1990;31(3):247-55.
PMID:1696747
Abstract
At a model of initial immunoresponse of mice to sheep erythrocytes the immunostimulating activity of lipopolysaccharide (LPS) and dextransulphate (DS) was tested. It was shown, that suppression of the immunosystem after influence of radiation can be compensated successfully by application of lipopolysaccharide and dextransulphate. The prophylactic application of these preparation is more ineffective.
摘要
在小鼠对绵羊红细胞的初始免疫反应模型中，测试了脂多糖（LPS）和硫酸葡聚糖（DS）的免疫刺激活性。结果表明，辐射影响后免疫系统的抑制可通过应用脂多糖和硫酸葡聚糖成功得到补偿。这些制剂的预防性应用效果较差。
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