Thalhammer J G, Stöckl W, Reyero C
Immunology. 1978 Nov;35(5):793-9.
The in vivo effects of Lipid A and dextran sulphate on the antibody response to the thymus-dependent antigen SRBC in piglets are reported. No alteration of the low primary antibody response was observed with any of the B-cell activators. However, both substances induced an increase in antibody titre after secondary challenge with the antigen, which was shown to be of the IgG class. An activation of immunological memory in the absence of primary antibody response is suggested.
报道了脂质A和硫酸葡聚糖对仔猪针对胸腺依赖性抗原绵羊红细胞（SRBC）的抗体反应的体内作用。未观察到任何B细胞激活剂对低水平的初次抗体反应有改变。然而，在用抗原再次攻击后，这两种物质均诱导抗体滴度增加，且显示为IgG类。提示在没有初次抗体反应的情况下免疫记忆被激活。
