Rabuka David, Hubbard Sarah C, Laughlin Scott T, Argade Sulabha P, Bertozzi Carolyn R
Department of Chemistry, University of California, Berkeley, California, USA.
J Am Chem Soc. 2006 Sep 20;128(37):12078-9. doi: 10.1021/ja064619y.
Fucosylated glycoproteins are involved in many cell-cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.
岩藻糖基化糖蛋白参与许多细胞间识别事件,是胚胎组织和恶性组织的标志物。在此,我们报告一种使用6-叠氮基岩藻糖作为代谢标记物从人细胞中快速分析岩藻糖基化糖蛋白的方法。