Cherqui D, Lauzet J Y, Rotman N, Duvoux C, Dhumeaux D, Julien M, Fagniez P L
Department of Surgery, Hôpital Henri Mondor, Université Paris XII, Créteil, France.
Transplantation. 1994 Oct 15;58(7):793-6.
Sixty-two OLTs in 61 patients were performed using a technical modification reported recently, including total hepatectomy with preservation of the inferior vena cava, partial clamping of the native vena cava, and side-to-side cavacaval anastomosis. We further modified the technique by adding the early construction of a temporary end-to-side portacaval shunt, and, more recently, by using an end-to-side caval reconstruction. With this technique, the caval and portal flows were maintained throughout the procedure. Hemodynamic parameters were analyzed prospectively during the operative period and remained stable at all stages of the procedure. Venous bypass was avoided in all cases without need for increased fluid infusion. Operative time and transfusion requirements were 6.8 +/- 1.6 hr and 9.8 +/- 4.3 U of packed RBC, respectively. There were no specific complications or deaths due to the technique used and hospital mortality was 10% (6/61). The technique used in this study is a safe adjunct to the technical armamentarium of clinical liver transplantation. Its main advantage seems to be hemodynamic stability throughout the procedure, obviating the need for venous bypass or fluid overload.
61例患者接受了62次肝移植手术,采用了最近报道的技术改良方法,包括保留肝后下腔静脉的全肝切除术、原位腔静脉部分阻断以及腔静脉端侧吻合。我们进一步改良了该技术,增加了早期建立临时性门腔静脉端侧分流,以及最近采用的腔静脉端侧重建术。采用该技术,整个手术过程中腔静脉和门静脉血流得以维持。术中对血流动力学参数进行了前瞻性分析,在手术各阶段均保持稳定。所有病例均避免了静脉转流,无需增加液体输注量。手术时间和红细胞输注量分别为6.8±1.6小时和9.8±4.3单位浓缩红细胞。未出现因所采用技术导致的特定并发症或死亡,医院死亡率为10%(6/61)。本研究中使用的技术是临床肝移植技术手段中的一种安全辅助方法。其主要优势似乎在于整个手术过程中的血流动力学稳定性,无需静脉转流或液体超负荷。