颅面骨巨细胞肉芽肿的CT与磁共振成像
CT and MR imaging of giant cell granuloma of the craniofacial bones.
作者信息
Nackos J S, Wiggins R H, Harnsberger H R
机构信息
Department of Radiology, University of Utah, Salt Lake City, Utah 84132, USA.
出版信息
AJNR Am J Neuroradiol. 2006 Sep;27(8):1651-3.
BACKGROUND AND PURPOSE
Giant cell granuloma (GCG) is a rare lesion. The purpose of this study was to determine the CT characteristics and describe possible MR imaging features of GCG of the craniofacial bones.
METHODS
We retrospectively reviewed 7 CT studies and 1 MR imaging study of 7 histologically proved cases of GCG in 2 men, 3 women, and 2 patients of unknown gender, aged 12-51 years, during a period of 10 years, from 1995 to 2005.
RESULTS
The granulomas predominantly involved the maxilla in 3 patients, the mandible in 2 patients, the temporal bone in 1 patient, and the nasal cavity in 1 patient. These lesions on imaging were expansile masses that demonstrated adjacent bone wall thinning, and most were associated with lytic bone destruction. They were predominantly masses with soft-tissue attenuation on CT scans and may have infiltrated the surrounding soft-tissue structures. The patient with an MR imaging had a lesion that was hypointense on both T1- and T2-weighted MR images. The lesions revealed avid homogeneous contrast enhancement.
CONCLUSION
The imaging features of GCG are nonspecific. However, this entity should be included in the differential diagnosis of expansile lesions in the craniofacial bones.
背景与目的
巨细胞肉芽肿（GCG）是一种罕见病变。本研究的目的是确定颅面骨GCG的CT特征并描述其可能的磁共振成像（MR）特征。
方法
我们回顾性分析了1995年至2005年期间10年间7例经组织学证实的GCG病例的7份CT研究资料和1份MR成像资料，其中男性2例，女性3例，性别不明者2例，年龄12至51岁。
结果
肉芽肿主要累及3例患者的上颌骨、2例患者的下颌骨、1例患者的颞骨和1例患者的鼻腔。这些病变在影像学上表现为膨胀性肿块，显示相邻骨壁变薄，且多数伴有骨质溶解破坏。在CT扫描上它们主要为软组织密度肿块，可能已浸润周围软组织结构。进行MR成像的患者其病变在T1加权和T2加权MR图像上均呈低信号。病变显示出明显的均匀强化。
结论
GCG的影像学特征是非特异性的。然而，在颅面骨膨胀性病变的鉴别诊断中应考虑到这一病变。
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