两种免疫相关泡沫逆转录病毒之间的分子差异：人类原型HSRV和黑猩猩分离株SFV6。
Molecular differences between two immunologically related spumaretroviruses: the human prototype HSRV and the chimpanzee isolate SFV6.
作者信息
Tobaly-Tapiero J, Santillana-Hayat M, Giron M L, Guillemin M C, Rozain F, Périès J, Emanoil-Ravier R
机构信息
Laboratoire des Rétrovirus et Rétrotransposons des Vertébrés, Hôpital Saint Louis, Paris, France.
出版信息
AIDS Res Hum Retroviruses. 1990 Jul;6(7):951-7. doi: 10.1089/aid.1990.6.951.
A comparative study at the genomic and protein level was performed between two immunologically related spumaretroviruses, the human HSRV and the simian SFV6. Cross immunoprecipitation analysis with specific polyclonal and monoclonal antisera indicates shared antigenic determinants. However, restriction analysis of the viral DNAs and thermal stability of the hybrids demonstrate that HSRV and SFV6 are two different isolates.
在基因组和蛋白质水平上对两种免疫相关的泡沫逆转录病毒——人类HSRV和猿猴SFV6进行了比较研究。用特异性多克隆和单克隆抗血清进行的交叉免疫沉淀分析表明存在共同的抗原决定簇。然而，病毒DNA的限制性分析和杂交体的热稳定性表明HSRV和SFV6是两种不同的分离株。
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