Sumthong Pattarawadee, Damveld Robbert A, Choi Young H, Arentshorst Mark, Ram Arthur F, van den Hondel Cees A, Verpoorte Rob
Division of Pharmacognosy, Section Metabolomics, Gorlaeus Laboratories, Institute of Biology, Leiden University, Leiden, The Netherlands.
Planta Med. 2006 Aug;72(10):943-4. doi: 10.1055/s-2006-946676.
Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. Centrifugal partition chromatography was used to isolate the active compounds. By (1)H-NMR the active compounds were identified as deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of 1,3 -alpha-D-glucan synthase were used as a cell wall damage model. The result showed that deoxylapachol from T. grandis extract induced fungal cell wall stress.
柚木(柚木属,马鞭草科)锯末提取物抑制了黑曲霉的生长。采用离心分配色谱法分离活性化合物。通过¹H-NMR鉴定活性化合物为去氧拉帕醇和柚木醌。使用两种显示1,3-α-D-葡聚糖合酶诱导的黑曲霉转基因菌株作为细胞壁损伤模型。结果表明,柚木提取物中的去氧拉帕醇诱导了真菌细胞壁应激。