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对其专利、化学成分和生物活性的全面综述。

A comprehensive review on its patents, chemical constituents, and biological activities.

作者信息

Asdaq Syed Mohammed Basheeruddin, Nayeem Naira, Alam Md Tauquir, Alaqel Saleh I, Imran Mohd, Hassan El-Waleed Elamin, Rabbani Syed Imam

机构信息

Department of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Dariyah, Riyadh 13713, Saudi Arabia.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Northern Border University, Rafha, Saudi Arabia.

出版信息

Saudi J Biol Sci. 2022 Mar;29(3):1456-1464. doi: 10.1016/j.sjbs.2021.11.026. Epub 2021 Nov 23.

Abstract

is a timber plant that is commonly referred to as teak. Its wide use as a medicine in the various indigenous systems makes it a plant of importance. A wide gamut of phytoconstituents like alkaloids, phenolic glycosides, steroids, etc. has been reported. A renewed interest in this plant has resulted in scientific investigations by various researchers towards the isolation and identification of active constituents along with scientific proof of its biological activities. The different parts of the plant have been scientifically evaluated for their antioxidant, antipyretic, analgesic, hypoglycemic, wound healing, cytotoxic, and many more biological activities. Documentation of this scientific knowledge is of importance to have consolidated precise information encompassing the various aspects of this plant, which could provide a base for future studies. This review is a compilation of the salient reports on these investigations concerning phytochemistry, the methods used to identify and quantify the constituents, the evaluation methods of the biological activity, toxicological studies, allergies and the patent/patent applications. This will further help researchers to find an area of the gap for future studies.

摘要

是一种木材植物,通常被称为柚木。它在各种本土医学体系中的广泛应用使其成为一种重要的植物。已经报道了多种植物成分,如生物碱、酚类糖苷、类固醇等。对这种植物的重新关注促使众多研究人员对其活性成分进行分离和鉴定,并对其生物活性进行科学验证。该植物的不同部位已针对其抗氧化、解热、镇痛、降血糖、伤口愈合、细胞毒性等多种生物活性进行了科学评估。记录这些科学知识对于整合有关该植物各个方面的精确信息非常重要,这可为未来的研究提供基础。本综述汇编了有关这些研究的重要报告,内容涉及植物化学、成分鉴定和定量方法、生物活性评估方法、毒理学研究、过敏以及专利/专利申请。这将进一步帮助研究人员找到未来研究的空白领域。

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