Luo Yingqin, Fu Cong, Zhang Da-Yong, Lin Kui
MOE Key Laboratory for Biodiversity Science and Ecological Engineering and College of Life Sciences, Beijing Normal University, Beijing 100875, China.
Trends Genet. 2006 Nov;22(11):593-6. doi: 10.1016/j.tig.2006.08.011. Epub 2006 Sep 12.
Phylogenies can be constructed in many ways, including using shared complex characters known as rare genomic changes (RGCs), such as insertions and deletions (indels), retroposon integrations and intron positions. Here, we demonstrate that distance-based phylogenies, which were determined by shared overlapping genes from 13 completely sequenced gamma-Proteobacteria genomes, are consistent with phylogenies based on 16S rRNAs and other robust markers. These findings suggest that overlapping genes could provide interesting additional insights into the phylogenomics of completely sequenced microbial genomes.
系统发育树可以通过多种方式构建，包括使用被称为罕见基因组变化（RGCs）的共享复杂特征，如插入和缺失（indels）、逆转座子整合和内含子位置。在这里，我们证明了基于距离的系统发育树，它由13个完全测序的γ-变形菌纲基因组中的共享重叠基因确定，与基于16S rRNA和其他可靠标记的系统发育树一致。这些发现表明，重叠基因可以为完全测序的微生物基因组的系统发育基因组学提供有趣的额外见解。
