Pokrovskaia S V, Korpachev V V, Komissarenko V P
Fiziol Zh (1978). 1990 May-Jun;36(3):67-71.
The effects of "splenic protein-free extract" and its fractions as well as splenin on the functional activity of the rat mast cells have been studied. It is established that this extract unlike splenin has no histamine-releasing activity, however it is able to inhibit histamine release from mast cels under the influence of specific liberator--substance 48/80. The found effect is associated with biologically active substances contained in fraction III of splenic protein-free extract.
已经研究了“脾脏无蛋白提取物”及其组分以及脾素对大鼠肥大细胞功能活性的影响。已确定，与脾素不同，这种提取物没有组胺释放活性，然而，在特异性释放剂——物质48/80的影响下，它能够抑制肥大细胞释放组胺。所发现的这种作用与脾脏无蛋白提取物的组分III中所含的生物活性物质有关。
