Nucci Marcio, Anaissie Elias
Hematology Service, Department of Internal Medicine, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Brazil.
Infect Dis Clin North Am. 2006 Sep;20(3):563-79. doi: 10.1016/j.idc.2006.06.002.
The hyalohyphomycetes (especially Fusarium spp) have emerged as significant pathogens in severely immunocompromised patients. Human infections by Fusarium spp can be superficial or limited to single organs in otherwise healthy patients. Such infections are rare and tend to respond well to therapy. By contrast, disseminated fusarial hyalohyphomycosis affects the immunocompromised host and frequently is fatal. Successful outcome is determined by the degree of immunosuppression and the extent of the infection. These infections may be suspected clinically on the basis of a constellation of clinical and laboratory findings, which should lead to prompt therapy.
透明丝孢霉病（尤其是镰刀菌属）已成为严重免疫功能低下患者的重要病原体。在其他方面健康的患者中，镰刀菌属引起的人类感染可能是浅表性的，或局限于单个器官。此类感染罕见，且往往对治疗反应良好。相比之下，播散性镰刀菌透明丝孢霉病会影响免疫功能低下的宿主，且常常是致命的。治疗成功与否取决于免疫抑制的程度和感染的范围。根据一系列临床和实验室检查结果，临床上可能怀疑存在这些感染，应立即进行治疗。
