Olsen Sonja J, Laosiritaworn Yongjua, Siasiriwattana Suvaj, Chunsuttiwat Supamit, Dowell Scott F
International Emerging Infections Program, Thai Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.
Int J Infect Dis. 2006 Nov;10(6):439-45. doi: 10.1016/j.ijid.2006.06.004. Epub 2006 Sep 20.
Pneumonia continues to be a leading infectious disease killer, yet accurately measuring incidence remains a challenge. In 2002, Thailand began active, population-based surveillance for radiographically confirmed pneumonia in Sa Kaeo Province.
Full-time surveillance officers conducted active case ascertainment at every hospital, and routine audits and a community cluster survey promoted complete and accurate reporting. A case of pneumonia was defined as acute infection with signs or symptoms of lower respiratory tract infection and evidence of new infiltrates. An independent panel of radiologists reviewed digital images of all radiographs.
Between September 2002 and August 2003, 777 patients met the case definition. The measured minimum incidence was 177/100,000 but the estimated incidence was as high as 580/100,000 with full adjustment for incomplete chest radiography and access to health care. Seventy-two (9%) patients died and 28% were known to be HIV positive. Fifteen (2%) patients had pneumonia twice during the year. The average cost of hospitalization for an episode of pneumonia ranged from US$490.80 to $628.60.
Pneumonia is a significant and costly public health problem in Thailand. This surveillance system allows precise assessment and monitoring of radiologically confirmed pneumonia and lays the groundwork for the introduction of new vaccines against pneumonia pathogens.
肺炎仍然是主要的感染性疾病致死原因,但准确测量发病率仍是一项挑战。2002年,泰国开始在北柳府开展基于人群的、针对影像学确诊肺炎的主动监测。
全职监测人员在每家医院进行主动病例排查,常规审计和社区群组调查促进了完整、准确的报告。肺炎病例定义为伴有下呼吸道感染体征或症状的急性感染以及有新的浸润影证据。一个由放射科医生组成的独立小组对所有X光片的数字图像进行了审查。
在2002年9月至2003年8月期间,777名患者符合病例定义。测量的最低发病率为177/10万,但在对胸部X光检查不完整和获得医疗服务情况进行全面调整后,估计发病率高达580/10万。72名(9%)患者死亡,已知28%为HIV阳性。15名(2%)患者在该年度内患肺炎两次。肺炎发作的平均住院费用在490.80美元至628.60美元之间。
肺炎在泰国是一个重大且代价高昂的公共卫生问题。该监测系统能够对影像学确诊的肺炎进行精确评估和监测,并为引入针对肺炎病原体的新疫苗奠定基础。