减数分裂中动粒附着的片面观点。

A one-sided view of kinetochore attachment in meiosis.

作者信息

Watanabe Yoshinori

机构信息

Laboratory of Chromosome Dynamics, Institute of Molecular and Cellular Biosciences, University of Tokyo, Yayoi, Tokyo 113-0032, Japan.

出版信息

Cell. 2006 Sep 22;126(6):1030-2. doi: 10.1016/j.cell.2006.09.005.

DOI:10.1016/j.cell.2006.09.005

PMID:16990129

Abstract

Meiosis includes a reductional division in which homologous chromosomes, rather than sister chromatids, are segregated to opposite poles of the spindle. In this issue of Cell, report that casein kinase 1 contributes to this process by promoting the attachment of both kinetochores of a homolog to only one pole of the meiotic spindle in budding yeast.

摘要

减数分裂包括一次减数分裂，其中同源染色体而非姐妹染色单体被分离到纺锤体的相对两极。在本期《细胞》杂志中，[研究人员]报道酪蛋白激酶1通过促进芽殖酵母中同源染色体的两个动粒仅附着于减数分裂纺锤体的一极来推动这一过程。