Kobrine A I, Evans D E, Rizzoli H V
J Neurosurg. 1977 Jul;47(1):57-63. doi: 10.3171/jns.1977.47.1.0057.
Blood flow in the spinal cord was measured in a group of monkeys over a wide range of artificially varied blood pressures after the administration of propranolol, a beta adrenergic blocker. Spinal cord blood flow was found to be constant and in the normal range between a mean system arterial blood pressure of 50 to 150 mm Hg. From 150 to 180 mm Hg spinal cord blood flow decreased. There was no breakthrough of autoregulation, previously seen in the untreated animal. It is suggested, therefore, that the previously observed breakthrough of autoregulation is a beta adrenergic-mediated phenomenon.
在一组猴子中，在给予β肾上腺素能阻滞剂普萘洛尔后，于广泛的人工改变的血压范围内测量脊髓血流。发现脊髓血流在平均系统动脉血压50至150毫米汞柱之间保持恒定且处于正常范围。从150至180毫米汞柱时，脊髓血流下降。未出现先前在未治疗动物中所见的自动调节突破现象。因此，有人提出，先前观察到的自动调节突破是一种β肾上腺素能介导的现象。
