Katz P S, Harris-Warrick R M
Department of Biochemistry, Brandeis University, Waltham, MA 02254-9110.
Trends Neurosci. 1990 Sep;13(9):367-73. doi: 10.1016/0166-2236(90)90021-2.
Recent work on neurons that release slow neuromodulators has revealed important generalities about the roles played by neuromodulation in motor systems. Activity of these cells can affect the cellular and synaptic properties of central pattern generating circuits, orchestrating new variations of motor patterns and sometimes coordinating their outputs with other motor patterns. Many modulatory neurons use multiple transmitters to evoke both fast and slow synaptic responses of various types in different target cells. Some modulatory cells can have a mediating as well as a modulating role, simultaneously acting as sensory neurons or components of another pattern generating circuit.
最近对释放慢速神经调质的神经元的研究揭示了神经调质在运动系统中所起作用的重要共性。这些细胞的活动可以影响中枢模式发生器回路的细胞和突触特性，编排运动模式的新变化，有时还能将其输出与其他运动模式进行协调。许多调制性神经元使用多种递质来在不同靶细胞中引发各种类型的快速和慢速突触反应。一些调制性细胞可以同时起到介导和调制的作用，既作为感觉神经元，又作为另一个模式发生器回路的组成部分。
