Katz P S
Department of Neurobiology and Anatomy, University of Texas Medical School, Houston 77225, USA.
Curr Opin Neurobiol. 1995 Dec;5(6):799-808. doi: 10.1016/0959-4388(95)80109-x.
Neuromodulation of motor circuits by extrinsic inputs provides enormous flexibility in the production of behavior. Recent work has shown that neurons intrinsic to central pattern-generating circuits can evoke neuromodulatory effects in addition to their neurotransmitting actions. Modulatory neurons often elicit a multitude of different effects attributable to actions at different receptors and/or through the release of co-transmitters. Differences in neuromodulation between species can account for differences in behavior. Modulation of neuromodulation may provide an additional level of flexibility to motor circuits.
外部输入对运动回路的神经调节为行为产生提供了巨大的灵活性。最近的研究表明，中枢模式发生器回路中的内在神经元除了其神经传递作用外，还能引发神经调节效应。调节性神经元通常会通过作用于不同受体和/或释放共递质而引发多种不同的效应。物种间神经调节的差异可以解释行为上的差异。对神经调节的调节可能为运动回路提供额外的灵活性。
