Ehntholt D J, Cerundolo D L, Bodek I, Schwope A D, Royer M D, Nielsen A P
Arthur D. Little, Inc., Cambridge, MA 02140.
Am Ind Hyg Assoc J. 1990 Sep;51(9):462-8. doi: 10.1080/15298669091369943.
The ASTM Standard Test Method for Resistance of Protective Clothing Materials to Permeation by Liquids and Gases (F 739-85) and the recommended permeation cell have been modified to permit the testing of protective clothing materials for permeation by the low volatility, low water solubility active ingredients present in many pesticide formulations. The modification makes use of solid collection medium, a thin (0.02-in. thick) sheet of silicone rubber, to collect permeants. Those compounds permeating the protective material can then be desorbed into an appropriate solvent and analyzed using conventional methods and instruments. A series of permeation tests have been conducted using samples of 10 common, commercially available protective glove materials and the modified cell. Permeation of the active ingredient as well as carrier solvent components of several concentrated pesticide formulations containing low volatility, low water solubility active ingredients and aromatic hydrocarbon carrier solvents has been monitored. The relative breakthrough and the total mass of material permeating the glove materials appears to be strongly related to the concentration of the aromatic carrier solvent present in the formulations studied to date. The collection method was found to be less useful for monitoring the permeation of active ingredients, which have reasonably high water solubilities. The results obtained by using this method with samples of protective glove materials challenged by several concentrated pesticide formulations are described. For these formulations containing xylene boiling range aromatic solvents, gloves made of nitrile rubber, butyl rubber, and Silver Shield were most resistant to permeation; natural rubber and polyethylene glove materials were least resistant.
美国材料与试验协会（ASTM）的防护服材料耐液体和气体渗透标准试验方法（F 739 - 85）及推荐的渗透池已作修改，以允许对防护服材料进行测试，检测其对许多农药制剂中存在的低挥发性、低水溶性活性成分的渗透性。此次修改采用固体收集介质，即一张薄（0.02英寸厚）的硅橡胶片，来收集渗透物。然后，那些渗透过防护服材料的化合物可解吸到适当的溶剂中，并使用常规方法和仪器进行分析。已使用10种常见的市售防护手套材料样品和改进后的渗透池进行了一系列渗透试验。监测了几种含有低挥发性、低水溶性活性成分和芳烃载体溶剂的浓缩农药制剂中活性成分以及载体溶剂成分的渗透情况。对于迄今为止所研究的制剂，相对突破量和透过手套材料的物质总量似乎与制剂中芳烃载体溶剂的浓度密切相关。结果发现，该收集方法对于监测水溶性较高的活性成分的渗透效果较差。描述了使用该方法对几种浓缩农药制剂挑战的防护手套材料样品进行测试所获得的结果。对于这些含有二甲苯沸程芳烃溶剂的制剂，丁腈橡胶、丁基橡胶和银盾制成的手套对渗透的抵抗力最强；天然橡胶和聚乙烯手套材料的抵抗力最弱。
