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抗磷脂综合征继发单侧肾上腺出血时的急性肾上腺功能不全

[Acute adrenal insufficiency during unilateral adrenal hemorrhage secondary to the antiphospholipid syndrome].

作者信息

Blanc P-L, Forel C, Jay S, Susset V

机构信息

Service de médecine D, centre hospitalier, 07103 Annonay, France.

出版信息

Rev Med Interne. 2006 Dec;27(12):970-2. doi: 10.1016/j.revmed.2006.07.009. Epub 2006 Aug 8.

Abstract

INTRODUCTION

Acute adrenal insufficiency during antiphospholipid syndrome is usually due to a bilateral adrenal hemorrhage. For a patient, an unilateral involvement has induced an acute adrenal insufficiency.

CASE REPORT

A patient with an antiphospholipid syndrome has developed an acute adrenal insufficiency with an unilateral adrenal hemorrhage. This complication was caused by a concurrent steroid therapy, for an associated lupus, which resulted in a suppression of the contralateral adrenal gland.

CONCLUSION

In patients with antiphospholipid syndrome and concurrent steroid therapy, usually for lupus, unilateral adrenal hemorrhage can cause acute adrenal insufficiency. Withdrawal of steroid might be difficult in case of undetected bilateral hemorrhage.

摘要

引言

抗磷脂综合征期间的急性肾上腺功能不全通常是由于双侧肾上腺出血所致。对于一名患者而言,单侧肾上腺受累引发了急性肾上腺功能不全。

病例报告

一名抗磷脂综合征患者出现了急性肾上腺功能不全并伴有单侧肾上腺出血。此并发症是由同时进行的针对相关狼疮的类固醇治疗引起的,该治疗导致对侧肾上腺受到抑制。

结论

在抗磷脂综合征且通常因狼疮而同时接受类固醇治疗的患者中,单侧肾上腺出血可导致急性肾上腺功能不全。若未检测到双侧出血,停用类固醇可能会很困难。

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