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伴有淀粉样沉积的垂体促黑素细胞瘤

Pituitary melanocorticotrophinoma with amyloid deposition.

作者信息

Bilbao J M, Kovacs K, Horvath E, Higgins H P, Horsey W J

出版信息

Can J Neurol Sci. 1975 Aug;2(3):199-202. doi: 10.1017/s0317167100020266.

DOI:10.1017/s0317167100020266
PMID:169979
Abstract

The light and electron microscopic features of a pituitary adenoma composed of adrenocorticotrophic hormone (ACTH) and melanocyte stimulating hormone (MSH) cells with perivascular amyloid deposition is reported. Histochemical and fine structural data indicate that this material is APUDamyloid and is present in the extra-cellular perivascular spaces. It is suggested that the differences in fine structure and of distribution of the amyloid in pituitary adenomas is dependent upon the cell of origin.

摘要

报告了一例由促肾上腺皮质激素(ACTH)和促黑素细胞激素(MSH)细胞组成并伴有血管周围淀粉样物质沉积的垂体腺瘤的光镜和电镜特征。组织化学和精细结构数据表明,这种物质是APUD细胞系淀粉样蛋白,存在于血管周围细胞外间隙。提示垂体腺瘤中淀粉样物质在精细结构和分布上的差异取决于其起源细胞。

相似文献

1
Pituitary melanocorticotrophinoma with amyloid deposition.伴有淀粉样沉积的垂体促黑素细胞瘤
Can J Neurol Sci. 1975 Aug;2(3):199-202. doi: 10.1017/s0317167100020266.
2
Concurrent production of adrenocorticotropin and prolactin from two distinct cell lines in a single pituitary adenoma: a detailed immunohistochemical analysis.单个垂体腺瘤中两种不同细胞系同时产生促肾上腺皮质激素和催乳素:详细的免疫组织化学分析
J Clin Endocrinol Metab. 1982 Nov;55(5):947-55. doi: 10.1210/jcem-55-5-947.
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Neoplasms of the anterior pituitary.垂体前叶肿瘤。
Neurosurgery. 1978 Jul-Aug;3(1):96-104. doi: 10.1227/00006123-197807000-00016.
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Immunocytochemical study of the hypophysis in 25 dogs with pituitary-dependent hyperadrenocorticism.对25只患有垂体依赖性肾上腺皮质功能亢进症的犬垂体进行免疫细胞化学研究。
Acta Endocrinol (Copenh). 1982 Sep;101(1):15-24. doi: 10.1530/acta.0.1010015.
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Accumulation of amyloid in pituitary adenomas.垂体腺瘤中淀粉样蛋白的积聚。
Acta Neuropathol. 1985;68(2):87-92. doi: 10.1007/BF00688628.
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Ultrastructural classification of pituitary adenomas.垂体腺瘤的超微结构分类
Can J Neurol Sci. 1976 Feb;3(1):9-21. doi: 10.1017/s0317167100025944.
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A case of pituitary somatotroph adenoma with concomitant secretion of growth hormone, prolactin, and adrenocorticotropic hormone--an adenoma derived from primordial stem cell, studied by immunohistochemistry, in situ hybridization, and cell culture.一例同时分泌生长激素、催乳素和促肾上腺皮质激素的垂体生长激素腺瘤——通过免疫组织化学、原位杂交和细胞培养研究的源自原始干细胞的腺瘤
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Surgical pathology of the pituitary: the adenomas. Part II.垂体的外科病理学:腺瘤。第二部分。
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Massive Crooke's hyalinization in corticotroph cell adenomas of the human pituitary. A histological, immunocytological, and electron microscopic study of three cases.人类垂体促肾上腺皮质激素细胞腺瘤中的大量克鲁克透明变性。3例的组织学、免疫细胞化学及电子显微镜研究
Acta Neurochir (Wien). 1981;58(3-4):235-43. doi: 10.1007/BF01407130.

引用本文的文献

1
Prolactin-derived amyloid in the aging pituitary gland.衰老垂体中催乳素衍生的淀粉样蛋白。
Am J Pathol. 1997 Jan;150(1):67-73.
2
Pituitary adenoma with amyloid deposits and hyperprolactinemia. Case report and review.伴有淀粉样沉积物和高催乳素血症的垂体腺瘤。病例报告及文献复习。
Acta Neuropathol. 1982;57(2-3):81-4. doi: 10.1007/BF00685373.