对甲硝唑和替硝唑耐药的阴道毛滴虫分离株的流行率。
Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole.
作者信息
Schwebke Jane R, Barrientes Frank J
机构信息
Department of Medicine, University of Alabama at Birmingham, ZRB 239, 1530 3rd Ave. S., Birmingham, AL 35294-0007, USA.
出版信息
Antimicrob Agents Chemother. 2006 Dec;50(12):4209-10. doi: 10.1128/AAC.00814-06. Epub 2006 Sep 25.
Abstract
Clinical isolates of Trichomonas vaginalis were obtained from women consecutively enrolled in a study of partner notification. Testing of susceptibility to metronidazole and tinidazole was performed. Resistance to metronidazole and tinidazole was present in 17/178 (9.6%) and 1/178 (0.56%) strains, respectively. In vitro resistance was poorly correlated with clinical response to treatment.
摘要
阴道毛滴虫的临床分离株取自连续纳入性伴侣通知研究的女性。进行了对甲硝唑和替硝唑的敏感性测试。分别有17/178（9.6%）和1/178（0.56%）的菌株对甲硝唑和替硝唑耐药。体外耐药性与治疗的临床反应相关性较差。
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本文引用的文献
1
Addition of treatment for trichomoniasis to syndromic management of urethritis in Malawi: a randomized clinical trial.
Sex Transm Dis. 2003 Jun;30(6):516-22. doi: 10.1097/00007435-200306000-00009.
2
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Antimicrob Agents Chemother. 2003 Apr;47(4):1407-9. doi: 10.1128/AAC.47.4.1407-1409.2003.
3
Prevalence of metronidazole-resistant Trichomonas vaginalis in a gynecology clinic.
J Reprod Med. 2001 Jun;46(6):545-9.
4
Prevalence of 5-nitroimidazole-resistant trichomonas vaginalis in Oviedo, Spain.
Sex Transm Dis. 2001 Feb;28(2):115-6. doi: 10.1097/00007435-200102000-00010.
5
Metronidazole-resistant vaginal trichomoniasis--an emerging problem.
N Engl J Med. 1999 Jul 22;341(4):292-3. doi: 10.1056/NEJM199907223410417.
6
Trichomonas vaginalis associated with low birth weight and preterm delivery. The Vaginal Infections and Prematurity Study Group.
Sex Transm Dis. 1997 Jul;24(6):353-60. doi: 10.1097/00007435-199707000-00008.
7
Non-ulcerative sexually transmitted diseases as risk factors for HIV-1 transmission in women: results from a cohort study.
AIDS. 1993 Jan;7(1):95-102. doi: 10.1097/00002030-199301000-00015.
8
In vitro drug susceptibility and doses of metronidazole required for cure in cases of refractory vaginal trichomoniasis.
J Infect Dis. 1986 May;153(5):948-55. doi: 10.1093/infdis/153.5.948.
9
In vitro susceptibility of Trichomonas vaginalis to metronidazole and treatment outcome in vaginal trichomoniasis.
Sex Transm Dis. 1988 Jan-Mar;15(1):17-24. doi: 10.1097/00007435-198801000-00004.
10
Strain of Trichomonas vaginalis resistant to metronidazole and other 5-nitroimidazoles.
Antimicrob Agents Chemother. 1979 Feb;15(2):254-7. doi: 10.1128/AAC.15.2.254.
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