Tsonis Panagiotis A
Department of Biology and Center for Tissue Regeneration and Engineering, University of Dayton, Ohio 45469-2320, USA.
J Anat. 2006 Oct;209(4):433-7. doi: 10.1111/j.1469-7580.2006.00634.x.
Evolution has used many different strategies to build eyes and lenses. However, the genetic regulation involved seems to be quite conserved. Likewise, the regeneration of eye structures is remarkable, especially in salamanders. This review outlines the basic mechanisms of lens regeneration and its induction and the possibility of creating lenses by transdifferentiation of the pigment epithelial cells, by stem cells or by bioengineering.
进化采用了许多不同的策略来构建眼睛和晶状体。然而，其中涉及的基因调控似乎相当保守。同样，眼睛结构的再生也很显著，尤其是在蝾螈中。这篇综述概述了晶状体再生及其诱导的基本机制，以及通过色素上皮细胞、干细胞或生物工程转分化来制造晶状体的可能性。
