Gandhi Megha, Chikindas Michael L
Department of Food Science, Rutgers, The State University of New Jersey, 65 Dudley Road, New Brunswick, NJ 08901, USA.
Int J Food Microbiol. 2007 Jan 1;113(1):1-15. doi: 10.1016/j.ijfoodmicro.2006.07.008. Epub 2006 Sep 28.
The foodborne pathogen Listeria is the causative agent of listeriosis, a severe disease with high hospitalization and case fatality rates. Listeria monocytogenes can survive and grow over a wide range of environmental conditions such as refrigeration temperatures, low pH and high salt concentration. This allows the pathogen to overcome food preservation and safety barriers, and pose a potential risk to human health. This review focuses on the key issues such as survival of the pathogen in adverse environments, and the important adaptation and survival mechanisms such as biofilm formation, quorum sensing and antimicrobial resistance. Studies on the development of technologies to prevent and control L. monocytogenes contamination in foods and food processing facilities are also discussed.
食源性病原体李斯特菌是李斯特菌病的病原体,这是一种具有高住院率和病死率的严重疾病。单核细胞增生李斯特菌能够在广泛的环境条件下生存和生长,如冷藏温度、低pH值和高盐浓度。这使得该病原体能够突破食品保鲜和安全屏障,对人类健康构成潜在风险。本综述重点关注病原体在不利环境中的存活等关键问题,以及生物膜形成、群体感应和抗菌耐药性等重要的适应和存活机制。还讨论了预防和控制食品及食品加工设施中单核细胞增生李斯特菌污染的技术发展研究。