Hoskin Peter J, Bownes Peter
Mount Vernon Cancer Centre, Middlesex, United Kingdom.
Semin Radiat Oncol. 2006 Oct;16(4):209-17. doi: 10.1016/j.semradonc.2006.04.003.
Brachytherapy has changed dramatically in the last decade, with the widespread introduction of high-dose rate afterloading systems having greater flexibility of source loading patterns and smaller sources enabling new anatomic sites to be considered. This has been harnessed to the major developments in cross-sectional imaging and dosimetry planning systems to enable highly conformal radiotherapy to be delivered accurately and reliably by brachytherapy. There has been a major change in the distribution of sites treated, the majority being prostate, gynecologic, and breast treatments, whereas an emerging role as a simple but effective palliative treatment in bronchus, esophagus, and rectal cancers has also been recognized.
在过去十年中，近距离放射治疗发生了巨大变化，高剂量率后装系统的广泛应用使得源加载模式具有更大的灵活性，且源尺寸更小，从而能够考虑新的解剖部位。这与横断面成像和剂量测定计划系统的重大发展相结合，使近距离放射治疗能够准确、可靠地实施高度适形的放射治疗。所治疗部位的分布发生了重大变化，大多数是前列腺、妇科和乳腺治疗，而在支气管癌、食管癌和直肠癌中作为一种简单但有效的姑息治疗的新作用也已得到认可。
