Ateh D D, Navsaria H A, Vadgama P
IRC in Biomedical Materials, Queen Mary University of London, London E14NS, UK.
J R Soc Interface. 2006 Dec 22;3(11):741-52. doi: 10.1098/rsif.2006.0141.
Polypyrrole (PPy) is a conjugated polymer that displays particular electronic properties including conductivity. In biomedical applications, it is usually electrochemically generated with the incorporation of any anionic species including also negatively charged biological macromolecules such as proteins and polysaccharides to give composite materials. In biomedical research, it has mainly been assessed for its role as a reporting interface in biosensors. However, there is an increasing literature on the application of PPy as a potentially electrically addressable tissue/cell support substrate. Here, we review studies that have considered such PPy based conducting polymers in direct contact with biological tissues and conclude that due to its versatile functional properties, it could contribute to a new generation of biomaterials.
聚吡咯（PPy）是一种具有特定电子特性（包括导电性）的共轭聚合物。在生物医学应用中，它通常通过电化学方法生成，并结合任何阴离子物种，包括带负电荷的生物大分子，如蛋白质和多糖，以制备复合材料。在生物医学研究中，它主要被评估为生物传感器中的报告界面。然而，关于PPy作为潜在的电可寻址组织/细胞支持基质的应用的文献越来越多。在这里，我们回顾了将此类基于PPy的导电聚合物与生物组织直接接触的研究，并得出结论，由于其多功能的功能特性，它可能有助于新一代生物材料的发展。
