de Miguel Bouzas Trinidad, Barros-Velázquez Jorge, Villa Tomás González
Department of Microbiology, Faculty of Pharmacy, University of Santiago de Compostela, E- 15782 Santiago de Compostela, Spain.
Protein Pept Lett. 2006;13(7):645-51. doi: 10.2174/092986606777790548.
Over the past two decades, research scientists have been involved in the investigation of thermophilic and hyperthermophilic microorganisms owing to the unique features of their enzymic systems. Such in-depth investigations are now on their way to mastering the cloning and industrial exploitation of a broad variety of genes encoding enzymes involved in starch hydrolysis, amino acid biosynthesis, protein hydrolysis, etc. In this work, we review the state of the art and future perspectives of industrial applications of enzymes from hyperthermophilic and extreme thermophilic microorganisms, special attention being paid to the biotechnological methods involved in their industrial exploitation.
在过去的二十年里，研究科学家们一直在研究嗜热和超嗜热微生物，因为它们的酶系统具有独特的特性。目前，此类深入研究正在掌握克隆和工业开发多种编码参与淀粉水解、氨基酸生物合成、蛋白质水解等过程的酶的基因。在这项工作中，我们综述了嗜热和极端嗜热微生物来源酶的工业应用现状及未来前景，特别关注了其工业开发中涉及的生物技术方法。
