Greifer Melanie K, Markowitz James F
Division of Pediatric Gastroenterology and Nutrition, Schneider Children's Hospital, 269-01 76th Avenue, New Hyde Park, New York 11040, USA.
Expert Opin Pharmacother. 2006 Oct;7(14):1907-18. doi: 10.1517/14656566.7.14.1907.
Ulcerative colitis is an important disease in the paediatric population. Ulcerative colitis is one of the chronic inflammatory bowel diseases, and is medically incurable. However, the arsenal of medications has grown as knowledge of the pathogenesis of this disease advances. This review looks at the classical treatments for children with ulcerative colitis, including the 5-aminosalicylates, corticosteroids and imunomodulators, as well as biological therapy and other, newer modalities.
溃疡性结肠炎是儿科人群中的一种重要疾病。溃疡性结肠炎是慢性炎症性肠病之一，医学上无法治愈。然而，随着对该疾病发病机制认识的进步，药物种类有所增加。本综述探讨了儿童溃疡性结肠炎的经典治疗方法，包括5-氨基水杨酸类药物、皮质类固醇和免疫调节剂，以及生物疗法和其他更新的治疗方式。
