Rey E, Moreno Elola-Olaso C, Rodríguez Artalejo F, Díaz-Rubio M
Department of Gastroenterology, Hospital Clínico San Carlos, Uninversidad Complutense, Madrid, Spain.
Rev Esp Enferm Dig. 2006 Jul;98(7):518-26. doi: 10.4321/s1130-01082006000700005.
To estimate the impact of gastroesophageal reflux (GER) symptoms on the utilization of healthcare services and work absenteeism in Spain.
A cross-sectional study on 2,500 subjects representative of the Spanish population from 40 to 79 years of age. Data were collected via a telephone interview in January 2002 using Locke s questionnaire after its cross-cultural adaptation and validation for telephone use in Spain.
GER is responsible for 296.8 doctor consultations (95% CI: 245.3-348.7) per 1,000 inhabitants per year, for 24 esophagogastrointestinal radiographic studies per 1,000 inhabitants per year (95% CI: 18-30), for 32.4 (95% CI: 25.5-39.3) high digestive endoscopies per 1,000 inhabitants per year, and for the loss of 201 (95% CI: 0-411.1) working days per 1,000 employed inhabitants with GER per year. In relation to medication intake, GER resulted in 4,092 (95% CI: 3,300-5,133) treatment days with H2 antagonists per 1,000 inhabitants per year, 9,030 (95% CI: 7,846-10,332) treatment days with proton pump inhibitors per 1,000 inhabitants per year, and 1,082 (95% CI: 519-1,549) treatment days with prokinetics per 1,000 inhabitants per year.
GER has a large impact on the utilization of healthcare resources and work absenteeism in Spain, in contrast to the widespread belief that it is an illness of little importance.
评估胃食管反流（GER）症状对西班牙医疗服务利用情况及工作缺勤的影响。
对2500名年龄在40至79岁之间、具有西班牙人口代表性的受试者进行横断面研究。2002年1月，在对Locke问卷进行跨文化改编并验证其适用于西班牙电话访谈后，通过电话访谈收集数据。
GER导致每年每1000名居民中有296.8次医生问诊（95%置信区间：245.3 - 348.7），每年每1000名居民中有24次食管胃肠道放射学检查（95%置信区间：18 - 30），每年每1000名居民中有32.4次（95%置信区间：25.5 - 39.3）高难度消化内镜检查，以及每年每1000名患有GER的就业居民中有201天（95%置信区间：0 - 411.1）的工作日损失。在药物摄入方面，GER导致每年每1000名居民中有4092天（95%置信区间：3300 - 5133）使用H2拮抗剂治疗，每年每1000名居民中有9030天（95%置信区间：7846 - 10332）使用质子泵抑制剂治疗，每年每1000名居民中有1082天（95%置信区间：519 - 1549）使用促动力药治疗。
与普遍认为GER是一种不太重要的疾病的观点相反，GER对西班牙的医疗资源利用和工作缺勤有很大影响。
