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中风后疾病感缺失:评估、发生率、亚型及其对功能结局的影响综述

Anosognosia after stroke: assessment, occurrence, subtypes and impact on functional outcome reviewed.

作者信息

Jehkonen M, Laihosalo M, Kettunen J

机构信息

Neurology and Rehabilitation, Tampere University Hospital, Tampere, Finland.

出版信息

Acta Neurol Scand. 2006 Nov;114(5):293-306. doi: 10.1111/j.1600-0404.2006.00723.x.

Abstract

PURPOSE

This review provides an update on recent research findings concerning the methods used in the assessment of anosognosia, the occurrence and subtypes of anosognosia, the association between anosognosia and neglect, and the impact of anosognosias on functional outcome.

METHODS

A systematic review covering the period from 1995 to 2005 was carried out on reports drawn from electronic databases (MEDLINE, PSYCHLIT) and identified from the references in these reports. Twenty-seven articles met the selection criteria.

RESULTS

The results of this review are in line with previous findings in the following respects: anosognosia was more often associated with right hemisphere damage, neglect and anosognosia co-occurred, and anosognosia had predictive value on poor functional outcome. The variation in the methods used in the assessment of anosognosia, patient samples and assessment times influence the occurrence rates and the predictive value of anosognosia, which might undermine the generalizability of the results.

CONCLUSIONS

More homogeneous patient samples and consistency in the assessment methods and evaluation times would facilitate comparisons of the occurrence and the impact of anosognosia on functional outcome. New methods need to be developed for the assessment of anosognosia. These new methods should take account of the subtypes of anosognosia both at verbal and at non-verbal levels.

摘要

目的

本综述提供了有关失认症评估方法、失认症的发生及亚型、失认症与忽视之间的关联以及失认症对功能结局影响的近期研究结果的最新信息。

方法

对1995年至2005年期间从电子数据库(MEDLINE、PSYCHLIT)获取的报告以及从这些报告的参考文献中识别出的报告进行了系统综述。27篇文章符合入选标准。

结果

本综述结果在以下方面与先前研究结果一致:失认症更常与右半球损伤相关,忽视和失认症同时出现,且失认症对不良功能结局具有预测价值。失认症评估方法、患者样本和评估时间的差异会影响失认症的发生率和预测价值,这可能会削弱结果的普遍性。

结论

更具同质性的患者样本以及评估方法和评估时间的一致性将有助于比较失认症的发生率及其对功能结局的影响。需要开发新的失认症评估方法。这些新方法应在言语和非言语层面考虑失认症的亚型。

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