Papadopoulou D, Louis C
Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology, Hellas, Crete, Greece.
Biochem Genet. 1990 Aug;28(7-8):337-46.
We have isolated the Drosophila melanogaster locus coding for L-glutamate dehydrogenase (EC 1.4.1.3) by virtue of its similarity to the corresponding human gene. There is only one copy of this gene in the fruit fly genome, located on the right arm of chromosome 3 (95D1-4). The transcript includes at least one large intron and matures to a approximately 2.4-kb-long polyadenylated RNA whose expression is under developmental control.
我们已通过与相应人类基因的相似性,分离出了果蝇中编码L-谷氨酸脱氢酶(EC 1.4.1.3)的基因座。在果蝇基因组中,该基因只有一个拷贝,位于3号染色体右臂(95D1-4)。该转录本至少包含一个大的内含子,并成熟为一个约2.4 kb长的多聚腺苷酸化RNA,其表达受发育调控。