Teodorovic I, Isabelle M, Carbone A, Passioukov A, Lejeune S, Jaminé D, Therasse P, Gloghini A, Dinjens W N M, Lam K H, Oomen M H A, Spatz A, Ratcliffe C, Knox K, Mager R, Kerr D, Pezzella F, van Damme B, van de Vijver M, van Boven H, Morente M M, Alonso S, Kerjaschki D, Pammer J, Lopez-Guerrero J A, Llombart Bosch A, van Veen E-B, Oosterhuis J W, Riegman P H J
EORTC Data Center, Avenue E. Mounier 83, B-1200 Brussels, Belgium.
Eur J Cancer. 2006 Dec;42(18):3110-6. doi: 10.1016/j.ejca.2006.04.033. Epub 2006 Oct 5.
Many systems have already been designed and successfully used for sharing histology images over large distances, without transfer of the original glass slides. Rapid evolution was seen when digital images could be transferred over the Internet. Nowadays, sophisticated Virtual Microscope systems can be acquired, with the capability to quickly scan large batches of glass slides at high magnification and compress and store the large images on disc, which subsequently can be consulted through the Internet. The images are stored on an image server, which can give simple, easy to transfer pictures to the user specifying a certain magnification on any position in the scan. This offers new opportunities in histology review, overcoming the necessity of the dynamic telepathology systems to have compatible software systems and microscopes and in addition, an adequate connection of sufficient bandwidth. Consulting the images now only requires an Internet connection and a computer with a high quality monitor. A system of complete pathology review supporting bio-repositories is described, based on the implementation of this technique in the European Human Frozen Tumor Tissue Bank (TuBaFrost).
已经设计出了许多系统，并成功用于远距离共享组织学图像，而无需传输原始玻璃切片。当数字图像可以通过互联网传输时，出现了快速发展。如今，可以购置先进的虚拟显微镜系统，该系统能够以高放大倍数快速扫描大批玻璃切片，并将大尺寸图像压缩并存储在磁盘上，随后可以通过互联网查阅这些图像。图像存储在图像服务器上，该服务器可以根据用户指定的扫描中任何位置的特定放大倍数，向用户提供简单、易于传输的图片。这为组织学检查带来了新机遇，克服了动态远程病理学系统需要兼容软件系统和显微镜以及充足带宽的适当连接的必要性。现在，查阅图像仅需要互联网连接和一台配有高质量显示器的计算机。基于该技术在欧洲人类冷冻肿瘤组织库（TuBaFrost）中的应用，描述了一个支持生物样本库的完整病理学检查系统。
