Schranz M Eric, Lysak Martin A, Mitchell-Olds Thomas
Department of Biology, Duke University, Durham, NC 27708, USA.
Trends Plant Sci. 2006 Nov;11(11):535-42. doi: 10.1016/j.tplants.2006.09.002. Epub 2006 Oct 6.
In this review we summarize recent advances in our understanding of phylogenetics, polyploidization and comparative genomics in the family Brassicaceae. These findings pave the way for a unified comparative genomic framework. We integrate several of these findings into a simple system of 24 conserved chromosomal blocks (labeled A-X). The naming, order, orientation and color-coding of these blocks are based on their positions in a proposed ancestral karyotype (n=8), rather than by their position in the reduced genome of Arabidopsis thaliana (n=5). We show how these crucifer building blocks can be rearranged to model the genome structures of A. thaliana, Arabidopsis lyrata, Capsella rubella and Brassica rapa. A framework for comparison between species is timely because several crucifer genome-sequencing projects are underway.
在本综述中，我们总结了近期在十字花科系统发育学、多倍体化和比较基因组学理解方面取得的进展。这些发现为统一的比较基因组框架铺平了道路。我们将其中一些发现整合到一个由24个保守染色体块（标记为A - X）组成的简单系统中。这些染色体块的命名、顺序、方向和颜色编码是基于它们在一个假定的祖先核型（n = 8）中的位置，而不是基于它们在拟南芥（n = 5）简化基因组中的位置。我们展示了这些十字花科构建模块如何重新排列以模拟拟南芥、琴叶拟南芥、微小拟南芥和白菜型油菜的基因组结构。由于几个十字花科基因组测序项目正在进行中，一个物种间比较的框架很及时。
