Gürtler R E, Cecere M C, Lauricella M A, Cardinal M V, Kitron U, Cohen J E
Laboratorio de Eco-Epidemiología, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
Parasitology. 2007 Jan;134(Pt 1):69-82. doi: 10.1017/S0031182006001259. Epub 2006 Oct 11.
The reservoir capacity of domestic cats and dogs for Trypanosoma cruzi infection and the host-feeding patterns of domestic Triatoma infestans were assessed longitudinally in 2 infested rural villages in north-western Argentina. A total of 86 dogs and 38 cats was repeatedly examined for T. cruzi infection by serology and/or xenodiagnosis. The composite prevalence of infection in dogs (60%), but not in cats, increased significantly with age and with the domiciliary density of infected T. infestans. Dogs and cats had similarly high forces of infection, prevalence of infectious hosts (41-42%), and infectiousness to bugs at a wide range of infected bug densities. The infectiousness to bugs of seropositive dogs declined significantly with increasing dog age and was highly aggregated. Individual dog infectiousness to bugs was significantly autocorrelated over time. Domestic T. infestans fed on dogs showed higher infection prevalence (49%) than those fed on cats (39%), humans (38%) or chickens (29%) among 1085 bugs examined. The basic reproduction number of T. cruzi in dogs was at least 8.2. Both cats and dogs are epidemiologically important sources of infection for bugs and householders, dogs nearly 3 times more than cats.
在阿根廷西北部两个受侵扰的乡村，对家猫和家犬感染克氏锥虫的储存能力以及家栖骚扰锥蝽的宿主取食模式进行了纵向评估。通过血清学和/或异种接种法，对总共86只狗和38只猫反复进行克氏锥虫感染检测。狗的综合感染率（60%）随年龄以及感染的骚扰锥蝽在住所内的密度增加而显著上升，而猫则不然。在各种感染锥蝽密度下，狗和猫的感染强度、感染宿主的患病率（41%-42%）以及对锥蝽的传染性都同样很高。血清学阳性的狗对锥蝽的传染性随狗龄增加而显著下降，且高度聚集。个体狗对锥蝽的传染性随时间显著自相关。在检查的1085只锥蝽中，以狗为宿主的家栖骚扰锥蝽的感染患病率（49%）高于以猫（39%）、人类（38%）或鸡（29%）为宿主的锥蝽。狗体内克氏锥虫的基本繁殖数至少为8.2。猫和狗在流行病学上都是锥蝽和住户重要的感染源，狗作为感染源的重要性几乎是猫的3倍。
